| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PPP2R2B/PP2A-B55 |
| Specificity: |
This antibody reacts specifically with PPP2R2B/PP2A-B55 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A group of proteins that are intimately involved in this process are the protein phosphatases, An additional protein phosphatase catalytic subunit, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity, Four major families of protein phosphatase catalytic subunits have been identified, Gamma and Delta) encoded by four distinct genes, In general, PP2A, PP2A-B55, PP2B (calcineurin) and PP2C, PPX (also known as PP4) is a putative member of a novel PP family, The B family of regulatory subunits (including B55, The PP2A catalytic subunit associates with a variety of regulatory subunits, The PP2A family comprises subfamily members PP2A&, a variable subunit and a catalytic subunit, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, and PP2Aâ, designated PP1, homeostasis and apoptosis, including division, is a B subfamily consisting of four B55 isoforms (Alpha, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, &circ, «, Beta, In eukaryotes, aring |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PR55-BETA PR52B |
| Also known as: |
PPP2R2B/PP2A-B55 Polyclonal Antibody |
| Other name: |
Anti-PPP2R2B/PP2A-B55 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PPP2R2B/PP2A-B55 |
| Short name: |
Anti-PPP2R2B/PP2A-B55 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, b/PP2A-B55 (polyclonal), regulatory functionnal sequence B, antibody to-protein phosphatase 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
B55BETA and PP2AB55BETA and PP2ABBETA and PP2APR55B and PP2APR55BETA and PR2AB55BETA and PR2ABBETA and PR2APR55BETA and PR52B and PR55-BETA and PR55BETA and SCA12, Cytoplasm, PPP2R2B and IDBG-52116 and ENSG00000156475 and 5521, PPP2R2B and IDBG-646174 and ENSBTAG00000001862 and 509290, Ppp2r2b and IDBG-143462 and ENSMUSG00000024500 and 72930, beta, protein phosphatase type 2A regulator activity, regulatory subunit B, this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0050790 and regulation of catalytic activity and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008601 : protein phosphatase type 2A regulator activity, this GO :0008601 : protein phosphatase type 2A regulator activity, protein phosphatase 2 |
| Identity: |
9305 |
| Gene: |
PPP2R2B |
More about : PPP2R2B |
| Long gene name: |
protein phosphatase 2 regulatory subunit Bbeta |
| Synonyms gene: |
SCA12 |
| Synonyms gene name: |
beta isoform , regulatory subunit B (PR 52), spinocerebellar ataxia 12 protein phosphatase 2 (formerly 2A) |
| Synonyms name: |
PP2A subunit B isoform beta |
| Locus: |
5q32 |
| Discovery year: |
1993-01-25 |
| GenBank acession: |
M64930 |
| Entrez gene record: |
5521 |
| Pubmed identfication: |
1849734 10581021 |
| RefSeq identity: |
NM_181678 |
| Classification: |
Protein phosphatase 2 regulatory subunits WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000163381 |