| Long name: |
PNP/Nucleoside phosphorylase Antibody |
| Also known as: |
PNP/Nucleoside phosphorylase Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PNP/Nucleoside phosphorylase |
| Specificity: |
This is a highly specific antibody against PNP/Nucleoside phosphorylase |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PNP/Nucleoside phosphorylase |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Children with PNP deficiency are highly prone to infections, Human PNP catalyzes the reversible phosphorolysis of ribonucleosides and 2â, It belongs to the PNP/MTAP phosphorylase family of proteins, PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, also designated inosine phosphorylase, and cancer, and their analogs, autoimmune disorders, comprising four percent of combined immunodeficiency cases, forms a homotrimer, hypoxanthine, neurological impairment, &euro, &trade, -deoxyribonucleosides with specificity for guanine, Purine nucleoside phosphorylase (PNP) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FLJ94043, FLJ97288, MGC117396, MGC125915, MGC125916, NP, Np1, Nucleoside phosphorylase, PNP, PNPH_HUMAN, PRO1837, PUNP, Pnp1, Purine nucleoside orthophosphate ribosyltransferase, Purine nucleoside phosphorylase, Inosine phosphorylase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PNP/Nucleoside phosphorylase |
| Short name: |
PNP/Nucleoside phosphorylase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
purine nucleoside phosphorylase/Nucleoside phosphorylase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, NP and PRO1837 and PUNP, PNP and IDBG-2272 and ENSG00000198805 and 4860, phosphate ion binding, this GO :0001882 and nucleoside binding and molecular function this GO :0002060 and purine nucleobase binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004731 and purine-nucleoside phosphorylase activity and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006139 and nucleobase-containing compound metabolic process and biological process this GO :0006144 and purine nucleobase metabolic process and biological process this GO :0006148 and inosine catabolic process and biological process this GO :0006195 and purine nucleotide catabolic process and biological process this GO :0006738 and nicotinamide riboside catabolic process and biological process this GO :0006955 and immune response and biological process this GO :0008144 and drug binding and molecular function this GO :0009116 and nucleoside metabolic process and biological process this GO :0034356 and NAD biosynthesis via nicotinamide riboside salvage pathway and biological process this GO :0034418 and urate biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042301 and phosphate ion binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043101 and purine-containing compound salvage and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070970 and interleukin-2 secretion and biological process, this GO :0001882 : nucleoside binding, this GO :0001882 : nucleoside binding and also this GO :0002060 : purine nucleobase binding and also this GO :0003824 : catalytic activity and also this GO :0004731 : purine-nucleoside phosphorylase activity and also this GO :0008144 : drug binding and also this GO :0042301 : phosphate ion binding, this GO :0002060 : purine nucleobase binding, this GO :0003824 : catalytic activity, this GO :0004731 : purine-nucleoside phosphorylase activity, this GO :0008144 : drug binding, this GO :0042301 : phosphate ion binding, purine nucleoside phosphorylase |
| Identity: |
9327 |
| Gene: |
PPY |
More about : PPY |
| Long gene name: |
pancreatic polypeptide |
| Synonyms: |
PNP |
| Synonyms name: |
pancreatic polypeptide Y prepro-PP (prepropancreatic polypeptide) |
| Locus: |
17q21, 31 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
5539 |
| Pubmed identfication: |
3753985 |
| RefSeq identity: |
NM_002722 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000181800 |