| Long name: |
FITC Conjugated, DGCR6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DGCR6 |
| Specificity: |
This is a highly specific antibody against DGCR6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DGCR6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, Due to a duplication of the ancestral DGCR6 locus, Expressed ubiquitously with highest levels in heart, The gene encoding DGCR6, Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, a developmental disorder characterized by improper facial, along with other DGCR genes, as well as in Burkittæ, both of which are involved in early tissue development, cardiac and palate formation, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22, is deleted in DiGeorge syndrome, liver and skeletal muscle, lymphoma and lymphocytes transformed by EBV, there are two functional, &Scaron, ¯, Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DGCR6 Conjugated |
| Short name: |
FITC Conjugated, DGCR6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DiGeorge syndrome critical region gene 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DGCR6 and IDBG-1186 and ENSG00000183628 and 102724770, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009887 and organ morphogenesis and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, 8214, DiGeorge syndrome critical region gene 6 |
| Identity: |
2846 |
| Gene: |
DGCR6 |
More about : DGCR6 |
| Long gene name: |
DiGeorge syndrome critical region gene 6 |
| Locus: |
22q11, 21 |
| Discovery year: |
2000-07-28 |
| GenBank acession: |
X96484 |
| Entrez gene record: |
8214 |
| Pubmed identfication: |
8733130 |
| RefSeq identity: |
NM_005675 |
| Havana BLAST/BLAT: |
OTTHUMG00000150162 |