| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DGCR6 |
| Specificity: |
This antibody reacts specifically with DGCR6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DGCR6 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, Due to a duplication of the ancestral DGCR6 locus, Expressed ubiquitously with highest levels in heart, The gene encoding DGCR6, Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, a developmental disorder characterized by improper facial, along with other DGCR genes, as well as in Burkittæ, both of which are involved in early tissue development, cardiac and palate formation, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22, is deleted in DiGeorge syndrome, liver and skeletal muscle, lymphoma and lymphocytes transformed by EBV, there are two functional, &Scaron, ¯, Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
DGCR6 Polyclonal Antibody |
| Other name: |
Anti-DGCR6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DGCR6 |
| Short name: |
Anti-DGCR6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DiGeorge syndrome critical region gene 6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DGCR6 and IDBG-1186 and ENSG00000183628 and 102724770, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005634 and nucleus and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009887 and organ morphogenesis and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function, 8214, DiGeorge syndrome critical region gene 6 |
| Identity: |
2846 |
| Gene: |
DGCR6 |
More about : DGCR6 |
| Long gene name: |
DiGeorge syndrome critical region gene 6 |
| Locus: |
22q11, 21 |
| Discovery year: |
2000-07-28 |
| GenBank acession: |
X96484 |
| Entrez gene record: |
8214 |
| Pubmed identfication: |
8733130 |
| RefSeq identity: |
NM_005675 |
| Havana BLAST/BLAT: |
OTTHUMG00000150162 |