| Long name: |
FITC Conjugated, CLN5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CLN5 |
| Specificity: |
This is a highly specific antibody against CLN5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CLN5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A single base duplication mutation in dog and cow CLN5 has been shown to cause NCL, CLN2 (encodeing the serine protease TPP1), CLN3, CLN5, CLN6 and CLN8, Mutations in six of these genes results in a distinct type of NCL-disease, NCL is characterized by atrophy of the brain and an accumulation of lysosome derived fluorescent bodies found in many cells, Symptoms of NCL include a failure of psychomotor development, The eight genes/proteins associated with NCL are designated CLN1-CLN8, a protein thiolesterase), also designated Batten disease, comprises a group of recessively inherited, especially neurons, impaired vision and premature death, progressive neurodegenerative diseases found in children, seizures, the six genes/proteins are CLN1 (encoding PPT1, Neuronal ceroid-lipofuscinose (NCL) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CLN5 Conjugated |
| Short name: |
FITC Conjugated, CLN5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CLN5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2076 |
| Gene: |
CLN5 |
More about : CLN5 |
| Long gene name: |
ceroid-lipofuscinosis, neuronal 5 |
| Locus: |
13q22, 3 |
| Discovery year: |
1993-11-03 |
| Entrez gene record: |
1203 |
| Pubmed identfication: |
7942847 8661106 |
| RefSeq identity: |
NM_006493 |
| Havana BLAST/BLAT: |
OTTHUMG00000017100 |
| Locus Specific Databases: |
NCL Mutations LRG_692 , Neuronal Ceroid Lipofuscinoses |