| Long name: |
ALEXA FLUOR 488 Conjugated, CLN5 Polyclonal Antibody |
| Also known as: |
Anti-CLN5 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CLN5 |
| Specificity: |
This is a highly specific antibody against CLN5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLN5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A single base duplication mutation in dog and cow CLN5 has been shown to cause NCL, CLN2 (encodeing the serine protease TPP1), CLN3, CLN5, CLN6 and CLN8, Mutations in six of these genes results in a distinct type of NCL-disease, NCL is characterized by atrophy of the brain and an accumulation of lysosome derived fluorescent bodies found in many cells, Symptoms of NCL include a failure of psychomotor development, The eight genes/proteins associated with NCL are designated CLN1-CLN8, a protein thiolesterase), also designated Batten disease, comprises a group of recessively inherited, especially neurons, impaired vision and premature death, progressive neurodegenerative diseases found in children, seizures, the six genes/proteins are CLN1 (encoding PPT1, Neuronal ceroid-lipofuscinose (NCL) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CLN5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CLN5 |
| Short name: |
CLN5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CLN5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2076 |
| Gene: |
CLN5 |
More about : CLN5 |
| Long gene name: |
ceroid-lipofuscinosis, neuronal 5 |
| Locus: |
13q22, 3 |
| Discovery year: |
1993-11-03 |
| Entrez gene record: |
1203 |
| Pubmed identfication: |
7942847 8661106 |
| RefSeq identity: |
NM_006493 |
| Havana BLAST/BLAT: |
OTTHUMG00000017100 |
| Locus Specific Databases: |
NCL Mutations LRG_692 , Neuronal Ceroid Lipofuscinoses |