| Long name: |
ALEXA FLUOR 488 Conjugated, AIP1 Polyclonal Antibody |
| Also known as: |
Anti-AIP1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIP1 |
| Specificity: |
This is a highly specific antibody against AIP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AIP1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), Expressed at low levels in prostate tissue, also known as DAB2IP (DAB2 interacting protein), disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, implicating a role for AIP1 fusion proteins in tumorigenesis, is a 1, one PH domain and one C2 domain, suggesting a role in tumor suppression, thereby allowing free ASK 1 to function within the cell, via this interaction, 189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, AIP1 (ASK-interacting protein 1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Alix AIP1 Hp95 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the AIP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
AIP1 |
| Short name: |
AIP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, AIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8766 |
| Gene: |
PDCD6IP |
More about : PDCD6IP |
| Long gene name: |
programmed cell death 6 interacting protein |
| Synonyms gene name: |
programmed cell death 6-interacting protein |
| Synonyms name: |
ALG-2 interacting protein X |
| Locus: |
3p22, 3 |
| Discovery year: |
1999-12-10 |
| GenBank acession: |
BC020066 |
| Entrez gene record: |
10015 |
| Pubmed identfication: |
9880530 |
| Havana BLAST/BLAT: |
OTTHUMG00000130751 |