| Long name: |
FITC Conjugated, FMR2/AFF2 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FMR2/AFF2 |
| Specificity: |
This is a highly specific antibody against FMR2/AFF2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human AFF2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, Expressed in the brain, FMR2 exists as two isoforms produced by alternative splicing, Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site, an X-linked form of mental retardation, compared to six to thirty-five copies of the GCC repeat in a normal individual, placenta and lung, FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FRAXE |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FMR2/AFF2 Conjugated |
| Short name: |
FITC Conjugated, FMR2/AFF2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FMR2/AFF2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3776 |
| Gene: |
AFF2 |
More about : AFF2 |
| Long gene name: |
AF4/FMR2 family member 2 |
| Synonyms gene: |
FMR2 |
| Synonyms gene name: |
fragile X mental retardation 2 AF4/FMR2 family, member 2 |
| Locus: |
Xq28 |
| Discovery year: |
2005-06-27 |
| GenBank acession: |
U48436 |
| Entrez gene record: |
2334 |
| RefSeq identity: |
NM_002025 |
| Classification: |
AF4/FMR2 family Super elongation complex |
| Havana BLAST/BLAT: |
OTTHUMG00000022613 |
| Locus Specific Databases: |
Mental Retardation database |