| Catalog number: | GENTAUR-58be5b9849bd9 |
|---|---|
| Price: | Ask price € |
| Supplier: | accurate-monoclonals |
| Product name: | Anti-FMR2/AFF2, ALEXA Fluor 594 |
| Quantity: | 1 vial |
| Related search: |
| Type: | Conjugated Primary Antibody |
|---|---|
| Conjugated with: | 594, ALEXA FLUOR® |
| Host organism: | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: | FMR2/AFF2 |
| Specificity: | This antibody reacts specifically with FMR2/AFF2 |
| Modification: | No modification has been applied to this antibody |
| Modification site: | None |
| Clonality: | Polyclonal Antibody |
| Clone: | Polyclonal Antibodies |
| Concentration: | 1ug per 1ul |
| Antigen Source: | KLH conjugated synthetic peptide derived from human AFF2 |
| Applications: | IF(IHC-P) |
| Applications with corresponding dilutions: | IF(IHC-P)(1:50-200) |
| Cross reactive species: | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: | Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, Expressed in the brain, FMR2 exists as two isoforms produced by alternative splicing, Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site, an X-linked form of mental retardation, compared to six to thirty-five copies of the GCC repeat in a normal individual, placenta and lung, FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family |
| Purification method: | Purified by Protein A |
| Storage: | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | FRAXE |
| Also known as: | FMR2/AFF2 Antibody |
| Other name: | Anti-FMR2/AFF2 |
| Advisory: | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: | For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | FMR2/AFF2 |
| Short name: | Fluor 594, Anti-FMR2/AFF2 |
| Label: | ALEXA |
| Alternative name: | ALEXA Fluor 594, antibody to-FMR2/AFF2 |
| Identity: | 3776 |
| Gene: | AFF2 | More about : AFF2 |
| Long gene name: | AF4/FMR2 family member 2 |
| Synonyms gene: | FMR2 |
| Synonyms gene name: | fragile X mental retardation 2 AF4/FMR2 family, member 2 |
| Locus: | Xq28 |
| Discovery year: | 2005-06-27 |
| GenBank acession: | U48436 |
| Entrez gene record: | 2334 |
| RefSeq identity: | NM_002025 |
| Classification: | AF4/FMR2 family Super elongation complex |
| Havana BLAST/BLAT: | OTTHUMG00000022613 |
| Locus Specific Databases: | Mental Retardation database |
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