| Long name: |
Presenilin 1 + 2 Primary Polyclonal Antibody |
| Also known as: |
Presenilin 1 + 2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Presenilin 1 + 2 |
| Specificity: |
This is a highly specific antibody against Presenilin 1 + 2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Presenilin-1/ Presenilin-2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
PSEN2) or the amyloid precursor protein (APP), Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains), an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP, Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AD4, AD5, Alzheimer disease 3, Alzheimer disease 4, FAD, PS-1, PS-2, PS1, PS2, PSEN1, PSEN2, PSN1_HUMAN, PSN2_HUMAN, Presenilin 1, Presenilin 2, Presenilin-1, Presenilin-2, Presenilin1, Presenilin1, STM2, AD 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Presenilin 1 + 2 |
| Short name: |
Presenilin 1 + 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Presenilin 1 and 2 (Antibody to) |
| Alternative technique: |
antibodies |