| Long name: |
ALEXA FLUOR 647 Conjugated, Aggrecan Polyclonal Antibody |
| Also known as: |
Anti-Aggrecan PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Aggrecan |
| Specificity: |
This is a highly specific antibody against Aggrecan |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-230/2415 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aggrecan |
| Swiss Prot: |
P16112 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage, Aggrecan in cartilage forms aggregates with hyaluronan and link protein, Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification, Aggrecan is a member of the chondroitin sulphate proteoglycan family, Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family, In the adult brain, Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage, aggrecan, embedded in a collagen network, is the predominant proteoglycan present in cartilage, neurocan and brevican, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment, which also includes versican/PG-M, The large chondroitin sulfate proteoglycan |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CSPGCP ACAN |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Aggrecan Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Aggrecan |
| Short name: |
Aggrecan Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Aggrecan (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7338 |
| Gene: |
MSK16 |
More about : MSK16 |
| Long gene name: |
aggrecan |
| Synonyms gene: |
CSPG1 AGC1 |
| Synonyms gene name: |
chondroitin sulfate proteoglycan 1 aggrecan 1 |
| Synonyms name: |
aggrecan proteoglycan |
| Locus: |
15q26, 1 |
| Discovery year: |
1992-06-17 |
| GenBank acession: |
M55172 |
| Entrez gene record: |
176 |
| Pubmed identfication: |
1985970 |
| RefSeq identity: |
NM_001135 |
| Classification: |
Sushi domain containing Hyalectan proteoglycans V-set domain containing C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171989 |