| Long name: |
ALEXA FLUOR 488 Conjugated, TMEM59 Polyclonal Antibody |
| Also known as: |
Anti-TMEM59 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMEM59 |
| Specificity: |
This is a highly specific antibody against TMEM59 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM59 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia, Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, Gaucher disease and Usher syndrome are also associated with chromosome 1, Notably, Parkinsons, Stickler syndrome, The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis, The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration, There are about 3, When defective, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, malignant melanoma and multiple myeloma, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A, 000 genes on chromosome 1, TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
HSPC001 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TMEM59 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TMEM59 |
| Short name: |
TMEM59 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, TMEM59 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1239 |
| Gene: |
TMEM59 |
More about : TMEM59 |
| Long gene name: |
transmembrane protein 59 |
| Synonyms gene: |
C1orf8 |
| Synonyms gene name: |
chromosome 1 open reading frame 8 |
| Locus: |
1p32, 3 |
| Discovery year: |
1999-07-22 |
| GenBank acession: |
AF047439 |
| Entrez gene record: |
9528 |
| Pubmed identfication: |
9653160 23376921 |
| RefSeq identity: |
NM_004872 |
| Havana BLAST/BLAT: |
OTTHUMG00000008437 |