| Long name: |
FITC Conjugated, TMEM59 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMEM59 |
| Specificity: |
This is a highly specific antibody against TMEM59 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TMEM59 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia, Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome, Gaucher disease and Usher syndrome are also associated with chromosome 1, Notably, Parkinsons, Stickler syndrome, The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis, The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration, There are about 3, When defective, and considering the great number of genes there are also a large number of diseases associated with chromosome 1, malignant melanoma and multiple myeloma, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A, 000 genes on chromosome 1, TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HSPC001 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMEM59 Conjugated |
| Short name: |
FITC Conjugated, TMEM59 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TMEM59 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1239 |
| Gene: |
TMEM59 |
More about : TMEM59 |
| Long gene name: |
transmembrane protein 59 |
| Synonyms gene: |
C1orf8 |
| Synonyms gene name: |
chromosome 1 open reading frame 8 |
| Locus: |
1p32, 3 |
| Discovery year: |
1999-07-22 |
| GenBank acession: |
AF047439 |
| Entrez gene record: |
9528 |
| Pubmed identfication: |
9653160 23376921 |
| RefSeq identity: |
NM_004872 |
| Havana BLAST/BLAT: |
OTTHUMG00000008437 |