| Long name: |
ALEXA FLUOR 488 Conjugated, Aph-1b Polyclonal Antibody |
| Also known as: |
Anti-Aph-1b PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Aph-1b |
| Specificity: |
This is a highly specific antibody against Aph-1b |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
75-125/257 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aph-1b |
| Gene ID Number: |
83464 |
| Swiss Prot: |
Q8WW43 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex, Probably present in a minority of gamma-secretase complexes compared to APH1A, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein), Probable subunit of the gamma-secretase complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PSFL APH-1B DKFZp564D0372 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Aph-1b Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Aph-1b |
| Short name: |
Aph-1b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Aph-1b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24080 |
| Gene: |
APH1B |
More about : APH1B |
| Long gene name: |
aph-1 homolog B, gamma-secretase subunit |
| Synonyms gene name: |
anterior pharynx defective 1 homolog B (C, elegans) APH1B gamma secretase subunit |
| Locus: |
15q22, 2 |
| Discovery year: |
2005-02-08 |
| GenBank acession: |
AY358698 |
| Entrez gene record: |
83464 |
| Pubmed identfication: |
12110170 11230166 |
| RefSeq identity: |
NM_031301 |
| Havana BLAST/BLAT: |
OTTHUMG00000132863 |