| Long name: |
FITC Conjugated, APBB3/FE65L2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APBB3/FE65L2 |
| Specificity: |
This is a highly specific antibody against APBB3/FE65L2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human APBB3/FE65L2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding to the intracellular domain of the â, Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Fe65L2 exists as four alternatively spliced isoforms designated isoform I, Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, Fe65L2 is thought to modulate the internalization and, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease, Via its ability to control the intracellular accumulation of â, isoform II, isoform III and isoform IV, the accessibility and function of â, therefore, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, &circ, &circ, &circ, «, «, «, -Amyloid, -Amyloid, -Amyloid precursor protein, Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FE65L2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APBB3/FE65L2 Conjugated |
| Short name: |
FITC Conjugated, APBB3/FE65L2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, APBB3/FE65L2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20708 |
| Gene: |
APBB3 |
More about : APBB3 |
| Long gene name: |
amyloid beta precursor protein binding family B member 3 |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family B, member 3 |
| Locus: |
5q31, 3 |
| Discovery year: |
2003-03-21 |
| GenBank acession: |
AB018247 |
| Entrez gene record: |
10307 |
| Pubmed identfication: |
9407065 |
| RefSeq identity: |
NM_006051 |