| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APBB3/FE65L2 |
| Specificity: |
This antibody reacts specifically with APBB3/FE65L2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APBB3/FE65L2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding to the intracellular domain of the â, Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Fe65L2 exists as four alternatively spliced isoforms designated isoform I, Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, Fe65L2 is thought to modulate the internalization and, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease, Via its ability to control the intracellular accumulation of â, isoform II, isoform III and isoform IV, the accessibility and function of â, therefore, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, &circ, &circ, &circ, «, «, «, -Amyloid, -Amyloid, -Amyloid precursor protein, Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FE65L2 |
| Also known as: |
APBB3/FE65L2 Polyclonal Antibody |
| Other name: |
Anti-APBB3/FE65L2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APBB3/FE65L2 |
| Short name: |
Anti-APBB3/FE65L2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APBB3/FE65L2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20708 |
| Gene: |
APBB3 |
More about : APBB3 |
| Long gene name: |
amyloid beta precursor protein binding family B member 3 |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family B, member 3 |
| Locus: |
5q31, 3 |
| Discovery year: |
2003-03-21 |
| GenBank acession: |
AB018247 |
| Entrez gene record: |
10307 |
| Pubmed identfication: |
9407065 |
| RefSeq identity: |
NM_006051 |