| Long name: |
FITC Conjugated, WBP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
WBP2 |
| Specificity: |
This is a highly specific antibody against WBP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human WBP2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, The domain mediates protein-protein interactions through the binding of polyproline ligands, The gene encoding WBP2 is located on human chromosome 17, WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2), colon, early onset breast cancer and a predisposition to cancers of the ovary, including structural, prostate gland and fallopian tubes, regulatory and signaling proteins, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
WBP-2 GRAMD6 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
WBP2 Conjugated |
| Short name: |
FITC Conjugated, WBP2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, WBP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12738 |
| Gene: |
WBP2 |
More about : WBP2 |
| Long gene name: |
WW domain binding protein 2 |
| Locus: |
17q25, 1 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
U79458 |
| Entrez gene record: |
23558 |
| Pubmed identfication: |
7644498 26881968 23233354 |
| RefSeq identity: |
NM_012478 |
| Classification: |
GRAM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179896 |