| Long name: |
FITC Conjugated, Glyt1/SLC6A9 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glyt1/SLC6A9 |
| Specificity: |
This is a highly specific antibody against Glyt1/SLC6A9 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, GlyT1 is found only in the white matter of the CNS, Specifically, The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3), The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5), Two different GlyT genes encode GlyT2 and GlyT1, each shows a unique pattern of expression (3, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31, 3 (3, 3), 4), 5, 5), 6), Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GLYT1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Glyt1/SLC6A9 Conjugated |
| Short name: |
FITC Conjugated, Glyt1/SLC6A9 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Glyt1/SLC6A9 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11056 |
| Gene: |
SLC6A9 |
More about : SLC6A9 |
| Long gene name: |
solute carrier family 6 member 9 |
| Synonyms gene name: |
glycine), member 9 , solute carrier family 6 (neurotransmitter transporter |
| Locus: |
1p34, 1 |
| Discovery year: |
1995-10-02 |
| GenBank acession: |
S70609 |
| Entrez gene record: |
6536 |
| Pubmed identfication: |
8183239 7587377 |
| RefSeq identity: |
NM_201649 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000008294 |