| Long name: |
Biotin Conjugated, Glyt1/SLC6A9 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glyt1/SLC6A9 |
| Specificity: |
This is a highly specific antibody against Glyt1/SLC6A9 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Glyt1/SLC6A9 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, GlyT1 is found only in the white matter of the CNS, Specifically, The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3), The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5), Two different GlyT genes encode GlyT2 and GlyT1, each shows a unique pattern of expression (3, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31, 3 (3, 3), 4), 5, 5), 6), Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
GLYT1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Glyt1/SLC6A9 Conjugated |
| Short name: |
Conjugated, Glyt1/SLC6A9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Glyt1/SLC6A9 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11056 |
| Gene: |
SLC6A9 |
More about : SLC6A9 |
| Long gene name: |
solute carrier family 6 member 9 |
| Synonyms gene name: |
glycine), member 9 , solute carrier family 6 (neurotransmitter transporter |
| Locus: |
1p34, 1 |
| Discovery year: |
1995-10-02 |
| GenBank acession: |
S70609 |
| Entrez gene record: |
6536 |
| Pubmed identfication: |
8183239 7587377 |
| RefSeq identity: |
NM_201649 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000008294 |