| Long name: |
FITC Conjugated, SOX8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SOX8 |
| Specificity: |
This is a highly specific antibody against SOX8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SOX8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
30 Sox genes have been identified, At present, Members of this family have been shown to be conserved during evolution and to play key roles during animal development, Some are involved in human diseases, Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes, The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages, These genes similarly contain sequences that encode for the HMG-box domain, including sex reversal, which is responsible for the sequence-specific DNA-binding activity, Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SOX8 Conjugated |
| Short name: |
FITC Conjugated, SOX8 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SRY (sex determining region Y)-box 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008584 and male this GO nad development and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010817 and regulation of hormone levels and biological process this GO :0014015 and positive regulation of gliogenesis and biological process this GO :0033690 and positive regulation of osteoblast proliferation and biological process this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044798 and nuclear transcription factor complex and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045662 and negative regulation of myoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046533 and negative regulation of photoreceptor cell differentiation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048469 and cell maturation and biological process this GO :0048484 and enteric nervous system development and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0060009 and Sertoli cell development and biological process this GO :0060018 and astrocyte fate commitment and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060221 and retinal rod cell differentiation and biological process this GO :0060612 and adipose tissue development and biological process this GO :0061138 and morphogenesis of a branching epithelium and biological process this GO :0072034 and renal vesicle induction and biological process this GO :0072197 and ureter morphogenesis and biological process this GO :0072289 and metanephric nephron tubule formation and biological process this GO :0090184 and positive regulation of kidney development and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process, SOX8 and IDBG-634123 and ENSBTAG00000020737 and 530317, SOX8 and IDBG-8450 and ENSG00000005513 and 30812, Sox8 and IDBG-152312 and ENSMUSG00000024176 and 20681, nuclei, protein heterodimerization activity, this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046982 : protein heterodimerization activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046982 : protein heterodimerization activity, SRY (sex determining region Y)-box 8 |
| Identity: |
11203 |
| Gene: |
SOX8 |
More about : SOX8 |
| Long gene name: |
SRY-box 8 |
| Synonyms gene name: |
SRY (sex determining region Y)-box 8 SRY box 8 |
| Locus: |
16p13, 3 |
| Discovery year: |
2000-03-14 |
| GenBank acession: |
AF164104 |
| Entrez gene record: |
30812 |
| Pubmed identfication: |
10662550 10684944 |
| Classification: |
SRY-boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000122101 |