| Long name: |
Biotin Conjugated, NAT8B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NAT8B |
| Specificity: |
This is a highly specific antibody against NAT8B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NAT8B |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A member of the camello family, A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, Human chromosome 2 consists of 237 million bases, NAT-8B (N-acetyltransferase 8B), NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13, Similarly, The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, a non-functional protein that is truncated in length, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, also known as CML2 (camello-like protein 2), as it causes the N-acetyltransferase to become disrupted, encodes over 1, is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation, sitosterolemia and Alstré, syndrome, which leads to a stop codon and subsequently, °, &permil, 2, 400 genes and makes up approximately 8% of the human genome, Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Hcml2 NAT8BP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NAT8B Conjugated |
| Short name: |
Conjugated, NAT8B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NAT8B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30235 |
| Gene: |
NAT8B |
More about : NAT8B |
| Long gene name: |
N-acetyltransferase 8B (putative, gene/pseudogene) |
| Synonyms gene name: |
N-acetyltransferase 8B (gene/pseudogene) N-acetyltransferase 8B (GCN5-related, gene/pseudogene) , putative |
| Locus: |
2p13, 1 |
| Discovery year: |
2006-10-24 |
| GenBank acession: |
BC069564 |
| Entrez gene record: |
51471 |
| Pubmed identfication: |
11397015 16395595 19011241 |
| RefSeq identity: |
NM_016347 |
| Havana BLAST/BLAT: |
OTTHUMG00000152811 |