| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NAT8B |
| Specificity: |
This antibody reacts specifically with NAT8B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NAT8B |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the camello family, A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, Human chromosome 2 consists of 237 million bases, NAT-8B (N-acetyltransferase 8B), NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13, Similarly, The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, a non-functional protein that is truncated in length, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, also known as CML2 (camello-like protein 2), as it causes the N-acetyltransferase to become disrupted, encodes over 1, is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation, sitosterolemia and Alstré, syndrome, which leads to a stop codon and subsequently, °, &permil, 2, 400 genes and makes up approximately 8% of the human genome, Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Hcml2 NAT8BP |
| Also known as: |
NAT8B Polyclonal Antibody |
| Other name: |
Anti-NAT8B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NAT8B |
| Short name: |
Anti-NAT8B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NAT8B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30235 |
| Gene: |
NAT8B |
More about : NAT8B |
| Long gene name: |
N-acetyltransferase 8B (putative, gene/pseudogene) |
| Synonyms gene name: |
N-acetyltransferase 8B (gene/pseudogene) N-acetyltransferase 8B (GCN5-related, gene/pseudogene) , putative |
| Locus: |
2p13, 1 |
| Discovery year: |
2006-10-24 |
| GenBank acession: |
BC069564 |
| Entrez gene record: |
51471 |
| Pubmed identfication: |
11397015 16395595 19011241 |
| RefSeq identity: |
NM_016347 |
| Havana BLAST/BLAT: |
OTTHUMG00000152811 |