| Long name: |
FITC Conjugated, LRP5L Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LRP5L |
| Specificity: |
This is a highly specific antibody against LRP5L |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human LRP5L |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
However, LRP is expressed in rat tibia, LRP5 affects bone mass accrual during growth, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family, LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway, LRP5 is most closely related to LRP1, LRP5L is a related protein that exists as two isoforms produced by alternative splicing, LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG), Of the known family members, VLDLR (very low density lipoprotein receptor) and ApoER2, YWTD repeats and an O-linked sugar domain, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, including LDLR (low density lipo-protein receptor), specifically in areas of the bone that are involved in remodeling, Members of the LDL receptor gene family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DKFZp434O0213 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LRP5L Conjugated |
| Short name: |
FITC Conjugated, LRP5L Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, low density lipoprotein receptor-related protein 5-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
LRP5L and IDBG-3018 and ENSG00000100068 and 91355, Wnt-activated receptor activity, multiple, this GO :0017147 and Wnt-protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process, this GO :0017147 : Wnt-protein binding, this GO :0017147 : Wnt-protein binding and also this GO :0042813 : Wnt-activated receptor activity, this GO :0042813 : Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5-like |
| Identity: |
25323 |
| Gene: |
LRP5L |
More about : LRP5L |
| Long gene name: |
LDL receptor related protein 5 like |
| Synonyms gene name: |
low density lipoprotein receptor-related protein 5-like |
| Locus: |
22q11, 23 |
| Discovery year: |
2005-10-09 |
| GenBank acession: |
AL137651 |
| Entrez gene record: |
91355 |
| RefSeq identity: |
NM_182492 |
| Havana BLAST/BLAT: |
OTTHUMG00000150900 |