| Long name: |
LRP5L Primary Polyclonal Antibody |
| Also known as: |
LRP5L PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LRP5L |
| Specificity: |
This is a highly specific antibody against LRP5L |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LRP5L |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
However, LRP is expressed in rat tibia, LRP5 affects bone mass accrual during growth, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family, LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway, LRP5 is most closely related to LRP1, LRP5L is a related protein that exists as two isoforms produced by alternative splicing, LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG), Of the known family members, VLDLR (very low density lipoprotein receptor) and ApoER2, YWTD repeats and an O-linked sugar domain, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, including LDLR (low density lipo-protein receptor), specifically in areas of the bone that are involved in remodeling, Members of the LDL receptor gene family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GP330, LRP-5-like, LRP5L, LRP5L_HUMAN, Low-density lipoprotein receptor-related protein 5-like protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LRP5L |
| Short name: |
LRP5L Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
low density lipoprotein receptor-related protein 5-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
LRP5L and IDBG-3018 and ENSG00000100068 and 91355, Wnt-activated receptor activity, multiple, this GO :0017147 and Wnt-protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0044332 and Wnt signaling pathway involved in dorsal/ventral axis specification and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process, this GO :0017147 : Wnt-protein binding, this GO :0017147 : Wnt-protein binding and also this GO :0042813 : Wnt-activated receptor activity, this GO :0042813 : Wnt-activated receptor activity, low density lipoprotein receptor-related protein 5-like |
| Identity: |
25323 |
| Gene: |
LRP5L |
More about : LRP5L |
| Long gene name: |
LDL receptor related protein 5 like |
| Synonyms gene name: |
low density lipoprotein receptor-related protein 5-like |
| Synonyms: |
DKFZp434O0213 |
| Locus: |
22q11, 23 |
| Discovery year: |
2005-10-09 |
| GenBank acession: |
AL137651 |
| Entrez gene record: |
91355 |
| RefSeq identity: |
NM_182492 |
| Havana BLAST/BLAT: |
OTTHUMG00000150900 |