| Long name: |
Biotin Conjugated, DISP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DISP2 |
| Specificity: |
This is a highly specific antibody against DISP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1150-1200/1401 |
| Subcellular location: |
Cell membrane |
| Source: |
KLH conjugated synthetic peptide derived from human DISP2 |
| Gene ID number: |
85455 |
| Swiss Prot: |
A7MBM2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At least two isoforms of DISP2 are known to exist, Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants, Hedgehog is a major player in signaling pathways during embryogenesis, It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells, Recently, and carcinogenesis and the DISP proteins have been implicated in these pathways, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish, tissue regeneration, DISP2 is the second of three known homologs of the D, melanogaster protein Dispatched |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
DISPB KIAA1742 HsT16908 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DISP2 Conjugated |
| Short name: |
Conjugated, DISP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, DISP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19712 |
| Gene: |
DISP2 |
More about : DISP2 |
| Long gene name: |
dispatched RND transporter family member 2 |
| Synonyms gene: |
LINC00594 C15orf36 |
| Synonyms gene name: |
dispatched homolog 2 (Drosophila) long intergenic non-protein coding RNA 594 chromosome 15 open reading frame 36 |
| Locus: |
15q15, 1 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AB051529 |
| Entrez gene record: |
85455 |
| Pubmed identfication: |
11214970 10619433 |
| RefSeq identity: |
NM_033510 |
| Havana BLAST/BLAT: |
OTTHUMG00000129983 |