| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DISP2 |
| Specificity: |
This antibody reacts specifically with DISP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DISP2 |
| Gene ID: |
85455 |
| Swiss Prot: |
A7MBM2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
At least two isoforms of DISP2 are known to exist, Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants, Hedgehog is a major player in signaling pathways during embryogenesis, It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells, Recently, and carcinogenesis and the DISP proteins have been implicated in these pathways, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish, tissue regeneration, DISP2 is the second of three known homologs of the D, melanogaster protein Dispatched |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DISPB KIAA1742 HsT16908 |
| Also known as: |
DISP2 Polyclonal Antibody |
| Other name: |
Anti-DISP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DISP2 |
| Short name: |
Anti-DISP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DISP2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19712 |
| Gene: |
DISP2 |
More about : DISP2 |
| Long gene name: |
dispatched RND transporter family member 2 |
| Synonyms gene: |
LINC00594 C15orf36 |
| Synonyms gene name: |
dispatched homolog 2 (Drosophila) long intergenic non-protein coding RNA 594 chromosome 15 open reading frame 36 |
| Locus: |
15q15, 1 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AB051529 |
| Entrez gene record: |
85455 |
| Pubmed identfication: |
11214970 10619433 |
| RefSeq identity: |
NM_033510 |
| Havana BLAST/BLAT: |
OTTHUMG00000129983 |