| Long name: |
Biotin Conjugated, RAI3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RAI3 |
| Specificity: |
This is a highly specific antibody against RAI3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human RAI3 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
RAI3 expression is upregulated in most tumor cell lines that express mutant p53, RAI3 is a potential molecular target for diagnosing breast cancer, RAI3 may also be involved in maintaining homeostasis of epithelial cells, Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation, and apoptosis, and selective suppression of signals from RAI3 may have a place in breast cancer treatments, cell growth, differentiation, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis, RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RAIG1 TIG1 PEIG-1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RAI3 Conjugated |
| Short name: |
Conjugated, RAI3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, RAI3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9836 |
| Gene: |
GPRC5A |
More about : GPRC5A |
| Long gene name: |
G protein-coupled receptor class C group 5 member A |
| Synonyms gene: |
RAI3 |
| Synonyms gene name: |
class C, group 5, member A , retinoic acid induced 3 G protein-coupled receptor |
| Locus: |
12p13, 1 |
| Discovery year: |
1999-01-12 |
| GenBank acession: |
AF095448 |
| Entrez gene record: |
9052 |
| Pubmed identfication: |
8832110 9857033 |
| RefSeq identity: |
NM_003979 |
| Classification: |
Class C orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000168710 |