| Long name: |
RAI3 Primary Polyclonal Antibody |
| Also known as: |
RAI3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RAI3 |
| Specificity: |
This is a highly specific antibody against RAI3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAI3 |
| Tested Applications: |
IF(IHC-P), IHC-P, FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
RAI3 expression is upregulated in most tumor cell lines that express mutant p53, RAI3 is a potential molecular target for diagnosing breast cancer, RAI3 may also be involved in maintaining homeostasis of epithelial cells, Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation, and apoptosis, and selective suppression of signals from RAI3 may have a place in breast cancer treatments, cell growth, differentiation, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis, RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
G-protein coupled receptor family C group 5 member A, GPCR 5A, GPCR5A, Gprc 5a, Gprc5a, Orphan G protein coupling receptor PEIG 1, Orphan G protein coupling receptor PEIG1, Orphan G-protein-coupling receptor PEIG-1, RAI 3, RAI3_HUMAN, RAIG-1, Raig 1, Raig1, Retinoic acid induced 3, Retinoic acid induced gene 1 protein, Retinoic acid induced protein 3, Retinoic acid responsive, Retinoic acid responsive gene, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3, G protein coupled receptor family C group 5 member A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RAI3 |
| Short name: |
RAI3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAI3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9836 |
| Gene: |
GPRC5A |
More about : GPRC5A |
| Long gene name: |
G protein-coupled receptor class C group 5 member A |
| Synonyms gene: |
RAI3 |
| Synonyms gene name: |
class C, group 5, member A , retinoic acid induced 3 G protein-coupled receptor |
| Synonyms: |
RAIG1 TIG1 PEIG-1 |
| Locus: |
12p13, 1 |
| Discovery year: |
1999-01-12 |
| GenBank acession: |
AF095448 |
| Entrez gene record: |
9052 |
| Pubmed identfication: |
8832110 9857033 |
| RefSeq identity: |
NM_003979 |
| Classification: |
Class C orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000168710 |