| Long name: |
PHOX2A/CFEOM2 Primary Polyclonal Antibody |
| Also known as: |
PHOX2A/CFEOM2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PHOX2A/CFEOM2 |
| Specificity: |
This is a highly specific antibody against PHOX2A/CFEOM2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PHOX2A |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
All enteric nervous system cells evolve from the neural crest, Both Phox2a and Phox2b are crucial for the regulation of endogenous tyrosine hydroxylase and dopamine-beta hydroxylase, In addition, In contrast, Phox2 proteins are sufficient to promote sympathetic neuron generation, Phox2a controls only the differentiation of the main noradrenergic center of the brain, Phox2b is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain, The cells that begin to differentiate along a neuronal lineage continue to express Phox2b, The gene which encodes Phox2a maps to human chromosome 11q13, and all cells that are undifferentiated initially express Phox2b, and begin to express Phox2a, paired-homeodomain transcription factors that are necessary for neuronal differentiation throughout the developing sympathetic, parasympathetic and enteric ganglia, the locus ceruleus, which are transiently expressed in neural crest cells, 3-q13, 4, Phox2a (also designated Arix1) and Phox2b are closely related |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARIX, ARIX 1 homeodomain protein, ARIX1 homeodomain protein, Aristaless homeobox gene homolog Drosophila, Aristaless homeobox homolog, Aristaless homeobox protein homolog, Arix homeodomain protein, CFEOM 2, CFEOM2, FEOM 2, FEOM2, Fibrosis of extraocular muscles congenital 2 autosomal recessive, MGC52227, NCAM 2, NCAM2, PHOX 2A, PHX2A_HUMAN, Paired like aristaless Homeobox 2A, Paired like homeobox 2a, Paired mesoderm homeobox 2a, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A, Phox2, Phox2a, Pmx 2a, Pmx2, Pmx2a, Aristaless homeobox Drosophila fibrosis of extraocular muscles congenital 2 autosomal recessive |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PHOX2A/CFEOM2 |
| Short name: |
PHOX2A/CFEOM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PHOX2A/CFEOM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
691 |
| Gene: |
PHOX2A |
More about : PHOX2A |
| Long gene name: |
paired like homeobox 2a |
| Synonyms gene: |
ARIX FEOM2 |
| Synonyms gene name: |
2, aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), autosomal recessive paired-like (aristaless) homeobox 2a , congenital, fibrosis of extraocular muscles |
| Synonyms: |
PMX2A CFEOM2 |
| Locus: |
11q13, 4 |
| Discovery year: |
1995-12-11 |
| GenBank acession: |
AF022722 |
| Entrez gene record: |
401 |
| Pubmed identfication: |
8661014 11600883 |
| RefSeq identity: |
NM_005169 |
| Classification: |
PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000167899 |