| Long name: |
FITC Conjugated, NR2E3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NR2E3 |
| Specificity: |
This is a highly specific antibody against NR2E3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NR2E3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in this gene encoding for the protein, NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development, NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located), The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors, cause enhanced S cone syndrome, which localizes to chromosome 15q22, 32, Photoreceptor-specific nuclear receptor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PNR rd7 RP37 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NR2E3 Conjugated |
| Short name: |
FITC Conjugated, NR2E3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NR2E3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7974 |
| Gene: |
NR2E3 |
More about : NR2E3 |
| Long gene name: |
nuclear receptor subfamily 2 group E member 3 |
| Synonyms gene name: |
group E, member 3 , nuclear receptor subfamily 2 |
| Locus: |
15q23 |
| Discovery year: |
1999-09-16 |
| Entrez gene record: |
10002 |
| Pubmed identfication: |
10220376 |
| RefSeq identity: |
NM_014249 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000172841 |
| Locus Specific Databases: |
Mutations of the Photoreceptor cell-specific Nuclear Receptor LOVD - Leiden Open Variation Database |