| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NR2E3 |
| Specificity: |
This antibody reacts specifically with NR2E3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NR2E3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in this gene encoding for the protein, NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development, NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located), The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors, cause enhanced S cone syndrome, which localizes to chromosome 15q22, 32, Photoreceptor-specific nuclear receptor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PNR rd7 RP37 |
| Also known as: |
NR2E3 Polyclonal Antibody |
| Other name: |
Anti-NR2E3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NR2E3 |
| Short name: |
Anti-NR2E3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NR2E3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7974 |
| Gene: |
NR2E3 |
More about : NR2E3 |
| Long gene name: |
nuclear receptor subfamily 2 group E member 3 |
| Synonyms gene name: |
group E, member 3 , nuclear receptor subfamily 2 |
| Locus: |
15q23 |
| Discovery year: |
1999-09-16 |
| Entrez gene record: |
10002 |
| Pubmed identfication: |
10220376 |
| RefSeq identity: |
NM_014249 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000172841 |
| Locus Specific Databases: |
Mutations of the Photoreceptor cell-specific Nuclear Receptor LOVD - Leiden Open Variation Database |