| Long name: |
Biotin Conjugated, LRRTM3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LRRTM3 |
| Specificity: |
This is a highly specific antibody against LRRTM3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human LRRTM3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All LRR repeats contain a variable segment and a highly conserved segment, As a result of alternative splicing events, Expressed in neuronal tissues, LRRTM family members are known to exhibit synaptogenic activity, LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid, LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, Localizing predominantly to the nervous system, The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development, allowing it to accommodate several leucine residues within a tightly packed core, and contains ten LRR repeats, the latter of which accounts for 11 or 12 residues of the entire LRR motif, two LRRTM3 isoforms exist, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LRRTM3 Conjugated |
| Short name: |
Conjugated, LRRTM3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, LRRTM3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19410 |
| Gene: |
LRRTM3 |
More about : LRRTM3 |
| Long gene name: |
leucine rich repeat transmembrane neuronal 3 |
| Locus: |
10q21, 3 |
| Discovery year: |
2004-02-04 |
| GenBank acession: |
BX640611 |
| Entrez gene record: |
347731 |
| Pubmed identfication: |
12676565 |
| RefSeq identity: |
NM_178011 |
| Havana BLAST/BLAT: |
OTTHUMG00000018332 |