| Long name: |
CSN7b Primary Polyclonal Antibody |
| Also known as: |
CSN7b PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CSN7b |
| Specificity: |
This is a highly specific antibody against CSN7b |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSN7b |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
COPS7a) or CSN7b (COP7b) and CSN8 (COP8), CSN2 (COPS2), CSN3, CSN3 (COPS3), CSN4, CSN4 (COPS4), CSN5, CSN5 (COPS5), CSN6, CSN6 (COP6), CSN7 is phosphorylated by CK2 and is composed of two subunits, CSN7a (COPS7, CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, CSN7b contains only a PCI region and is predicted to interact with INT6, CSN8, I&, It is also involved in the phosphorylation of p53, The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, The complex is made up of several widely expressed proteins: CSN1 (COPS1), a and b, and GPS1, and IRF-8, and c-Jun protects and promotes degradation by the Ubl system, as well as CSN-dependent phosphorylation of p53, as well as a coiled-coil region and is predicted to interact with CSN2, c-Jun, which leads to a decrease in ubiquitin ligase activity of SCF-complexes, #730, B&, The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes, aring |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
COP9 Constitutive Photomorphogenic Homolog Subunit 7b, COP9 Signalasome Subunit 7b, COP9 signalosome complex subunit 7b, COPS7B, CSN7B_HUMAN, JAB1 Containing Signalosome Subunit 7b, JAB1-containing signalosome subunit 7b, SGN7b, Signalosome subunit 7b, COP9 Complex Homolog Subunit 7b |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CSN7b |
| Short name: |
CSN7b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CSN7b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16760 |
| Gene: |
COPS7B |
More about : COPS7B |
| Long gene name: |
COP9 signalosome subunit 7B |
| Synonyms gene name: |
Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 7B COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) |
| Synonyms: |
CSN7B |
| Locus: |
2q37, 1 |
| Discovery year: |
2001-10-03 |
| GenBank acession: |
AK022674 |
| Entrez gene record: |
64708 |
| Pubmed identfication: |
9707402 |
| RefSeq identity: |
NM_022730 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000133228 |