| Long name: |
FITC Conjugated, TUB 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TUB 1 |
| Specificity: |
This is a highly specific antibody against TUB 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TUB 1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
(5) and Bardet-Biedl (6), A Gè, A candidate for the tub gene has been described (4), A second prematurely truncated mRNA transcript with the unspliced intron was found to be expressed in the brains of tubby mice at a 2-3 fold higher rate as compared to B6 mice (4), In addition to excessive deposition of adipose tissue, It has been postulated that the phenotypic features of tubby mice can be attributed to cellular apoptosis triggered by the expression of a mutated tub gene (4), The tripartite character of tubby phenotype is strikingly similar to human obesity syndromes such as Alstré, mice with the tub phenotype also suffer retinal degeneration and neurosensory hearing loss (4-6), mutations in the tub gene lead to obesity gradually and strongly resemble late-onset obesity as seen in the human population (4), transversion in this candidate gene eliminates a donor splice site in the 3' coding region resulting in a larger transcript containing an unspliced intron (4), &Scaron, °, &ldquo, &permil, In contrast to the rapid early-onset weight gain seen in ob/ob mice (1-3) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
rd5 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TUB 1 Conjugated |
| Short name: |
FITC Conjugated, TUB 1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, tubby homolog (mouse) 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
TUB and IDBG-30462 and ENSG00000166402 and 7275, TUB and IDBG-633715 and ENSBTAG00000004862 and 539051, Tub and IDBG-206024 and ENSMUSG00000031028 and 22141, nuclei, protein complex binding, rd5, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0007602 and phototransduction and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008020 and G-protein coupled photoreceptor activity and molecular function this GO :0009584 and detection of visible light and biological process this GO :0009725 and response to hormone and biological process this GO :0032403 and protein complex binding and molecular function this GO :0044259 and multicellular organismal macromolecule metabolic process and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0060041 and retina development in camera-type eye and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008020 : G-protein coupled photoreceptor activity and also this GO :0032403 : protein complex binding, this GO :0008020 : G-protein coupled photoreceptor activity, this GO :0032403 : protein complex binding, tubby homolog (mouse) |
| Identity: |
12406 |
| Gene: |
TUB |
More about : TUB |
| Long gene name: |
tubby bipartite transcription factor |
| Synonyms gene name: |
tubby (mouse) homolog tubby homolog (mouse) |
| Locus: |
11p15, 4 |
| Discovery year: |
1996-10-11 |
| GenBank acession: |
U54644 |
| Entrez gene record: |
7275 |
| Pubmed identfication: |
8612280 |
| RefSeq identity: |
NM_003320 |
| Havana BLAST/BLAT: |
OTTHUMG00000165690 |