| Long name: |
FITC Conjugated, CCKAR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCKAR |
| Specificity: |
This is a highly specific antibody against CCKAR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
178-210/428 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CCKAR |
| Gene ID number: |
886 |
| Swiss Prot: |
P32238 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Chicken, Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Has a 1000-fold higher affinity for CCK rather than for gastrin, It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system, Mediates pancreatic growth and enzyme secretion, This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system, smooth muscle contraction of the gall bladder and stomach, Receptor for cholecystokinin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCKAR Conjugated |
| Short name: |
FITC Conjugated, CCKAR Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, cholecystokinin A receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCK-A and CCK1-R and CCK1R and CCKRA, CCKAR and IDBG-12723 and ENSG00000163394 and 886, CCKAR and IDBG-641476 and ENSBTAG00000004988 and 506207, Cckar and IDBG-164710 and ENSMUSG00000029193 and 12425, Plasma membranes, cholecystokinin receptor activity, this GO :0001764 and neuron migration and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004951 and cholecystokinin receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007409 and axonogenesis and biological process this GO :0007584 and response to nutrient and biological process this GO :0007586 and digestion and biological process this GO :0007631 and feeding behavior and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030900 and forebrain development and biological process this GO :0038188 and cholecystokinin signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004951 : cholecystokinin receptor activity, this GO :0004951 : cholecystokinin receptor activity, cholecystokinin A receptor |
| Identity: |
1570 |
| Gene: |
CCKAR |
More about : CCKAR |
| Long gene name: |
cholecystokinin A receptor |
| Locus: |
4p15, 2 |
| Discovery year: |
1993-07-13 |
| GenBank acession: |
L19315 |
| Entrez gene record: |
886 |
| Classification: |
Cholecystokinin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000128567 |