| Long name: |
FITC Conjugated, ZNF312B/FEZF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ZNF312B/FEZF1 |
| Specificity: |
This is a highly specific antibody against ZNF312B/FEZF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ZNF312B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
FEZF1 (Fez family zinc finger protein 1), In FEZF1-deficient mice, Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumor mass in mice, There are three isoforms of FEZF1 that are produced as a result of alternative splicing events, When FEZF1 translocates to the nucleus, also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, axons of olfactory neurons do not reach the olfactory bulb, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice, it induces KRAS overexpression, resulting in activation of ERK-signaling, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules, which is covered by the CNS basal lamina, Olfactory sensory neurons contain olfactory receptors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ZNF312B/FEZF1 Conjugated |
| Short name: |
FITC Conjugated, ZNF312B/FEZF1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ZNF312B/FEZF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
22788 |
| Gene: |
FEZF1 |
More about : FEZF1 |
| Long gene name: |
FEZ family zinc finger 1 |
| Synonyms gene: |
ZNF312B |
| Synonyms gene name: |
zinc finger protein 312B |
| Locus: |
7q31, 32 |
| Discovery year: |
2006-08-14 |
| GenBank acession: |
AY726588 |
| Entrez gene record: |
389549 |
| RefSeq identity: |
NM_001024613 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000157091 |