| Long name: |
ALEXA FLUOR 350 Conjugated, ZNF312B/FEZF1 Polyclonal Antibody |
| Also known as: |
Anti-ZNF312B/FEZF1 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ZNF312B/FEZF1 |
| Specificity: |
This is a highly specific antibody against ZNF312B/FEZF1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZNF312B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
FEZF1 (Fez family zinc finger protein 1), In FEZF1-deficient mice, Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumor mass in mice, There are three isoforms of FEZF1 that are produced as a result of alternative splicing events, When FEZF1 translocates to the nucleus, also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, axons of olfactory neurons do not reach the olfactory bulb, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice, it induces KRAS overexpression, resulting in activation of ERK-signaling, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules, which is covered by the CNS basal lamina, Olfactory sensory neurons contain olfactory receptors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ZNF312B/FEZF1 |
| Short name: |
ZNF312B/FEZF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, ZNF312B/FEZF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
22788 |
| Gene: |
FEZF1 |
More about : FEZF1 |
| Long gene name: |
FEZ family zinc finger 1 |
| Synonyms gene: |
ZNF312B |
| Synonyms gene name: |
zinc finger protein 312B |
| Locus: |
7q31, 32 |
| Discovery year: |
2006-08-14 |
| GenBank acession: |
AY726588 |
| Entrez gene record: |
389549 |
| RefSeq identity: |
NM_001024613 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000157091 |