| Long name: |
FITC Conjugated, Torsin A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torsin A |
| Specificity: |
This is a highly specific antibody against Torsin A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Torsin A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Early-onset torsion dystonia is a movement disorder, Symptoms are believed to result from altered neuronal communication in the basal ganglia, The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family, The gene which encodes TorsinA maps to human chromosome 9q34, The proteins display cytoplasmic distribution, TorsinA comprises 332 amino acids, TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions, TorsinA often performs chaperone-like functions that assist in the assembly, although in some types of neurons localization is perinuclear, characterized by twisting muscle contractures, has been identified as the cause of one form of autosomal dominantly inherited dystonia, operation, or dis-assembly of protein complexes, that begins in childhood, which codes for TorsinA, A mutation of the DYT1 gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Dystonia 1, Dystonia 1 protein, Dyt1, TOR1A_HUMAN, Tor1a, Torsin A, Torsin family 1 member A, DQ2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torsin A Conjugated |
| Short name: |
FITC Conjugated, Torsin A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Torsin A (Antibody to) |
| Alternative technique: |
antibodies |