| Long name: |
Cy3 Conjugated, Torsin A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torsin A |
| Specificity: |
This is a highly specific antibody against Torsin A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Torsin A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Early-onset torsion dystonia is a movement disorder, Symptoms are believed to result from altered neuronal communication in the basal ganglia, The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family, The gene which encodes TorsinA maps to human chromosome 9q34, The proteins display cytoplasmic distribution, TorsinA comprises 332 amino acids, TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions, TorsinA often performs chaperone-like functions that assist in the assembly, although in some types of neurons localization is perinuclear, characterized by twisting muscle contractures, has been identified as the cause of one form of autosomal dominantly inherited dystonia, operation, or dis-assembly of protein complexes, that begins in childhood, which codes for TorsinA, A mutation of the DYT1 gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
Dystonia 1, Dystonia 1 protein, Dyt1, TOR1A_HUMAN, Tor1a, Torsin A, Torsin family 1 member A, DQ2 |
| Properties: |
1 of the Torsin A Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torsin A Conjugated |
| Short name: |
Conjugated, Torsin A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Torsin A (Antibody to) |
| Alternative technique: |
antibodies |