| Long name: |
AACS/ACSF1 Primary Polyclonal Antibody |
| Also known as: |
AACS/ACSF1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AACS/ACSF1 |
| Specificity: |
This is a highly specific antibody against AACS/ACSF1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AACS |
| Gene ID number: |
65985 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis, ACSF1 is highly expressed in kidney, ACSF1 participates in ATP binding, Encoded by a gene that maps to human chromosome 12q24, Existing as three alternatively spliced isoforms, The ACSF1 promoter is a known PPAR?target gene, acetoacetate-CoA ligase activity and nucleotide binding, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase), heart and brain, ligase activity, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1), 31, ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AACS_HUMAN, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, Acetoacetyl-CoA synthetase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AACS/ACSF1 |
| Short name: |
AACS/ACSF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
acetoacetyl-CoA synthetase/ACSF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AACS and IDBG-631841 and ENSBTAG00000005678 and 505842, AACS and IDBG-64292 and ENSG00000081760 and 65985, Aacs and IDBG-201420 and ENSMUSG00000029482 and 78894, Cytoplasm, butyrate-CoA ligase activity, this GO :0001889 and liver development and biological process this GO :0003824 and catalytic activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0007584 and response to nutrient and biological process this GO :0008152 and metabolic process and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014074 and response to purine-containing compound and biological process this GO :0030729 and acetoacetate-CoA ligase activity and molecular function this GO :0032024 and positive regulation of insulin secretion and biological process this GO :0034201 and response to oleic acid and biological process this GO :0042493 and response to drug and biological process this GO :0042594 and response to starvation and biological process this GO :0045471 and response to ethanol and biological process this GO :0047760 and butyrate-CoA ligase activity and molecular function this GO :0050872 and white fat cell differentiation and biological process this GO :0060612 and adipose tissue development and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071394 and cellular response to testosterone stimulus and biological process this GO :0071397 and cellular response to cholesterol and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0005524 : ATP binding and also this GO :0030729 : acetoacetate-CoA ligase activity and also this GO :0047760 : butyrate-CoA ligase activity, this GO :0005524 : ATP binding, this GO :0030729 : acetoacetate-CoA ligase activity, this GO :0047760 : butyrate-CoA ligase activity, acetoacetyl-CoA synthetase |
| Identity: |
21298 |
| Gene: |
AACS |
More about : AACS |
| Long gene name: |
acetoacetyl-CoA synthetase |
| Synonyms: |
FLJ12389 SUR-5 ACSF1 |
| Synonyms name: |
acyl-CoA synthetase family member 1 |
| Locus: |
12q24, 31 |
| Discovery year: |
2003-06-02 |
| GenBank acession: |
AK022451 |
| Entrez gene record: |
65985 |
| Pubmed identfication: |
12623130 17762044 |
| RefSeq identity: |
NM_023928 |
| Classification: |
Acyl-CoA synthetase family |
| Havana BLAST/BLAT: |
OTTHUMG00000168550 |