| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AACS/ACSF1 |
| Specificity: |
This antibody reacts specifically with AACS/ACSF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AACS |
| Gene ID: |
65985 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis, ACSF1 is highly expressed in kidney, ACSF1 participates in ATP binding, Encoded by a gene that maps to human chromosome 12q24, Existing as three alternatively spliced isoforms, The ACSF1 promoter is a known PPAR?target gene, acetoacetate-CoA ligase activity and nucleotide binding, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase), heart and brain, ligase activity, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1), 31, ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ12389 SUR-5 ACSF1 |
| Also known as: |
AACS/ACSF1 Polyclonal Antibody |
| Other name: |
Anti-AACS/ACSF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AACS/ACSF1 |
| Short name: |
Anti-AACS/ACSF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-acetoacetyl-CoA synthetase/ACSF1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AACS and IDBG-631841 and ENSBTAG00000005678 and 505842, AACS and IDBG-64292 and ENSG00000081760 and 65985, Aacs and IDBG-201420 and ENSMUSG00000029482 and 78894, Cytoplasm, butyrate-CoA ligase activity, this GO :0001889 and liver development and biological process this GO :0003824 and catalytic activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0007584 and response to nutrient and biological process this GO :0008152 and metabolic process and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014074 and response to purine-containing compound and biological process this GO :0030729 and acetoacetate-CoA ligase activity and molecular function this GO :0032024 and positive regulation of insulin secretion and biological process this GO :0034201 and response to oleic acid and biological process this GO :0042493 and response to drug and biological process this GO :0042594 and response to starvation and biological process this GO :0045471 and response to ethanol and biological process this GO :0047760 and butyrate-CoA ligase activity and molecular function this GO :0050872 and white fat cell differentiation and biological process this GO :0060612 and adipose tissue development and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071394 and cellular response to testosterone stimulus and biological process this GO :0071397 and cellular response to cholesterol and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0005524 : ATP binding and also this GO :0030729 : acetoacetate-CoA ligase activity and also this GO :0047760 : butyrate-CoA ligase activity, this GO :0005524 : ATP binding, this GO :0030729 : acetoacetate-CoA ligase activity, this GO :0047760 : butyrate-CoA ligase activity, acetoacetyl-CoA synthetase |
| Identity: |
21298 |
| Gene: |
AACS |
More about : AACS |
| Long gene name: |
acetoacetyl-CoA synthetase |
| Synonyms name: |
acyl-CoA synthetase family member 1 |
| Locus: |
12q24, 31 |
| Discovery year: |
2003-06-02 |
| GenBank acession: |
AK022451 |
| Entrez gene record: |
65985 |
| Pubmed identfication: |
12623130 17762044 |
| RefSeq identity: |
NM_023928 |
| Classification: |
Acyl-CoA synthetase family |
| Havana BLAST/BLAT: |
OTTHUMG00000168550 |