| Long name: |
Biotin Conjugated, BEGAIN/SAPAP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BEGAIN/SAPAP |
| Specificity: |
This is a highly specific antibody against BEGAIN/SAPAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human BEGAIN |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BEGAIN and SAPAP may compete for the binding to PSD-95 and cannot interact with PSD-95 simultaneously, BEGAIN interacts with PSD-95 and SAPAP1 and forms a ternary complex and may sustain the structure of the postsynaptic density (PSD), BEGAIN is a novel PSD component associated with the core complex of PSD-95 and SAPAP, BEGAIN is also expressed in neurons and enriched at synaptic junctions, BEGAIN is specifically expressed in brain and enriched in the PSD fraction, Because BEGAIN and SAPAP interact with the same region of PSD-95, The C-terminal region of BEGAIN is involved in the interaction with PSD-95 whereas the N-terminal region has a coiled-coil structure that may interact with other molecules, and is likely involved in the organization of synaptic junction components, BEGAIN is a 593 amino acid protein that localizes to cytoplasm and membrane |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA1446 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BEGAIN/SAPAP Conjugated |
| Short name: |
Conjugated, BEGAIN/SAPAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, BEGAIN/SAPAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24163 |
| Gene: |
BEGAIN |
More about : BEGAIN |
| Long gene name: |
brain enriched guanylate kinase associated |
| Synonyms gene name: |
brain-enriched guanylate kinase-associated homolog (rat) brain-enriched guanylate kinase-associated |
| Locus: |
14q32, 2 |
| Discovery year: |
2007-08-16 |
| GenBank acession: |
BC002607 |
| Entrez gene record: |
57596 |
| Pubmed identfication: |
10819331 |
| RefSeq identity: |
NM_020836 |
| Havana BLAST/BLAT: |
OTTHUMG00000171589 |