| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BEGAIN/SAPAP |
| Specificity: |
This antibody reacts specifically with BEGAIN/SAPAP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BEGAIN |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BEGAIN and SAPAP may compete for the binding to PSD-95 and cannot interact with PSD-95 simultaneously, BEGAIN interacts with PSD-95 and SAPAP1 and forms a ternary complex and may sustain the structure of the postsynaptic density (PSD), BEGAIN is a novel PSD component associated with the core complex of PSD-95 and SAPAP, BEGAIN is also expressed in neurons and enriched at synaptic junctions, BEGAIN is specifically expressed in brain and enriched in the PSD fraction, Because BEGAIN and SAPAP interact with the same region of PSD-95, The C-terminal region of BEGAIN is involved in the interaction with PSD-95 whereas the N-terminal region has a coiled-coil structure that may interact with other molecules, and is likely involved in the organization of synaptic junction components, BEGAIN is a 593 amino acid protein that localizes to cytoplasm and membrane |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1446 |
| Also known as: |
BEGAIN/SAPAP Polyclonal Antibody |
| Other name: |
Anti-BEGAIN/SAPAP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BEGAIN/SAPAP |
| Short name: |
Anti-BEGAIN/SAPAP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BEGAIN/SAPAP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24163 |
| Gene: |
BEGAIN |
More about : BEGAIN |
| Long gene name: |
brain enriched guanylate kinase associated |
| Synonyms gene name: |
brain-enriched guanylate kinase-associated homolog (rat) brain-enriched guanylate kinase-associated |
| Locus: |
14q32, 2 |
| Discovery year: |
2007-08-16 |
| GenBank acession: |
BC002607 |
| Entrez gene record: |
57596 |
| Pubmed identfication: |
10819331 |
| RefSeq identity: |
NM_020836 |
| Havana BLAST/BLAT: |
OTTHUMG00000171589 |