| Long name: |
FITC Conjugated, SORCS1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SORCS1 |
| Specificity: |
This is a highly specific antibody against SORCS1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SORCS1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues, Alternative splicing of murine SorCS1 also results in four isoforms, Human SorCS1 is detected in fetal and infant brain and in fetal retina, In the developing and mature central nervous system, It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex, Murine isoform 1 is highly expressed in brain and at lower levels in heart, Murine isoform 2 is highly expressed in liver and at lower levels in heart, SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain, based on a common VPS10 domain, brain, kidney and testis, liver and kidney, non-overlapping pattern, partially overlapping functions in the central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, which is the hallmark of the SorCS receptor family, There are three sorCS genes that have diverse |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
sorCS1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SORCS1 Conjugated |
| Short name: |
FITC Conjugated, SORCS1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SORCS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16697 |
| Gene: |
SORCS1 |
More about : SORCS1 |
| Long gene name: |
sortilin related VPS10 domain containing receptor 1 |
| Synonyms gene name: |
sortilin-related VPS10 domain containing receptor 1 |
| Locus: |
10q25, 1 |
| Discovery year: |
2004-04-20 |
| GenBank acession: |
AF284756 |
| Entrez gene record: |
114815 |
| Pubmed identfication: |
11499680 |
| RefSeq identity: |
NM_052918 |
| Havana BLAST/BLAT: |
OTTHUMG00000019018 |