| Long name: |
SORCS1 Primary Polyclonal Antibody |
| Also known as: |
SORCS1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SORCS1 |
| Specificity: |
This is a highly specific antibody against SORCS1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SORCS1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues, Alternative splicing of murine SorCS1 also results in four isoforms, Human SorCS1 is detected in fetal and infant brain and in fetal retina, In the developing and mature central nervous system, It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex, Murine isoform 1 is highly expressed in brain and at lower levels in heart, Murine isoform 2 is highly expressed in liver and at lower levels in heart, SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain, based on a common VPS10 domain, brain, kidney and testis, liver and kidney, non-overlapping pattern, partially overlapping functions in the central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, which is the hallmark of the SorCS receptor family, There are three sorCS genes that have diverse |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FLJ41758, FLJ43475, FLJ44957, OTTHUMP00000058855, SORC1_HUMAN, SORCS, SORCS receptor 1, SORCS-1, Sortilin related VPS10 domain containing receptor 1, VPS10 domain containing receptor SorCS1, VPS10 domain receptor SorCS, VPS10 domain receptor protein SORCS, VPS10 domain receptor protein SORCS 1, VPS10 domain receptor protein SORCS1, hSorCS, SorCS 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SORCS1 |
| Short name: |
SORCS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SORCS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16697 |
| Gene: |
SORCS1 |
More about : SORCS1 |
| Long gene name: |
sortilin related VPS10 domain containing receptor 1 |
| Synonyms gene name: |
sortilin-related VPS10 domain containing receptor 1 |
| Synonyms: |
sorCS1 |
| Locus: |
10q25, 1 |
| Discovery year: |
2004-04-20 |
| GenBank acession: |
AF284756 |
| Entrez gene record: |
114815 |
| Pubmed identfication: |
11499680 |
| RefSeq identity: |
NM_052918 |
| Havana BLAST/BLAT: |
OTTHUMG00000019018 |