| Long name: |
ALEXA FLUOR 647 Conjugated, Islet 2 Polyclonal Antibody |
| Also known as: |
Anti-Islet 2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Islet 2 |
| Specificity: |
This is a highly specific antibody against Islet 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Islet 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character, Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates, Islet-2 is a nuclear protein that contains two N-terminal LIM domains, Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways, Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character, Somatic, but not visceral, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus, motor neurons maintain Islet-2 expression at later embryonic stages, Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Islet 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Islet 2 |
| Short name: |
Islet 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Islet 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14442 |
| Gene: |
ICA1L |
More about : ICA1L |
| Long gene name: |
islet cell autoantigen 1 like |
| Synonyms gene: |
ALS2CR15 ALS2CR14 |
| Synonyms gene name: |
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 14 islet cell autoantigen 1, candidate 15 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, 69kDa-like |
| Locus: |
2q33, 2 |
| Discovery year: |
2001-01-26 |
| GenBank acession: |
AB053317 |
| Entrez gene record: |
130026 |
| Pubmed identfication: |
11586298 |
| RefSeq identity: |
NM_138468 |
| Classification: |
Classical BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132856 |