| Long name: |
ALEXA FLUOR 488 Conjugated, Islet-1+2 Polyclonal Antibody |
| Also known as: |
Anti-Islet-1+2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Islet-1+2 |
| Specificity: |
This is a highly specific antibody against Islet-1+2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Islet-1/2 |
| Gene ID Number: |
3670 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In developing mouse teeth, Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry, Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium, Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord, Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner, Islet-1 and Islet-2 contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ISL LIM homeobox 1, ISL1, ISL1 transcription factor, ISL1 transcription factor, ISL1 transcription factor LIM homeodomain, ISL1_HUMAN, Insulin gene enhancer protein ISL-1, Insulin related protein, Isl 1, Islet-1, Islet1, LIM/homeodomain, LIM/homeodomain islet 1, Insulin gene enhancer protein ISL 1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Islet-1+2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Islet-1+2 |
| Short name: |
Islet-1+2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Islet-1+2 (Antibody to) |
| Alternative technique: |
antibodies |