| Long name: |
PE Conjugated, TPOR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
PE |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TPOR |
| Specificity: |
This is a highly specific antibody against TPOR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TPOR |
| Tested applications: |
FCM |
| Recommended dilutions: |
FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Expression of c-Mpl is restricted to hematopoietic tissues and cells, Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, TPO exerts its biological effects through the TPO receptor, Tyk 2 and JAK2, also known as c-Mpl ligand (c-Mpl L), c-Mpl, c-Mpl is a member of the cytokine receptor superfamily, causing their nuclear translocation and the transcription of Stat responsive genes, fetal liver and CD34+ cells, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome, is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells, spleen, such as bone marrow, which in turn phosphorylate Stat5 and Stat3, Thrombopoietin (TPO or THPO) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
480, 565nm/578nm |
| Synonyms: |
CD110 TPOR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TPOR PE Conjugated |
| Short name: |
PE Conjugated, TPOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
PE |
| Alternative name: |
peroxidase coupled, TPOR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7217 |
| Gene: |
MPL |
More about : MPL |
| Long gene name: |
MPL proto-oncogene, thrombopoietin receptor |
| Synonyms gene name: |
myeloproliferative leukemia virus oncogene |
| Locus: |
1p34, 2 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
M90102 |
| Entrez gene record: |
4352 |
| Pubmed identfication: |
1608974 |
| RefSeq identity: |
NM_005373 |
| Classification: |
CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000007429 |
| Locus Specific Databases: |
LRG_510 |