| Long name: |
FITC Conjugated, TCTEL1/DYNLT1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TCTEL1/DYNLT1 |
| Specificity: |
This is a highly specific antibody against TCTEL1/DYNLT1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TCTEL1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell, Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, Cytoplasmic or axonemal Dynein heavy, It performs functions necessary for cell survival such as organelle transport and centrosome assembly, LIS1 and NudEL(NudE-like), Several proteins regulate Dynein activity, Tctex1, Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A), The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, also designated CW-1 or TCTEL1 is expressed in heart, four smaller intermediate chains and several light chains, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement, ileum and colon, including dynactin, intermediate, kidney, light and light-intermediate chains are all components of minus end-directed motors, ovary, pancreas, placenta, prostate, skeletal muscle, spleen, testis, the complex transports cellular cargos towards the central region of the cell, two intermediate chains to anchor Dynein to its cargo, while the amino terminal regions are more variable, Dyneins are multisubunit |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TCTEL1/DYNLT1 Conjugated |
| Short name: |
FITC Conjugated, TCTEL1/DYNLT1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
Tctex-classification 1 (Antibody to), fluorecein coupled, light epitope, TCTEL1/dynein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CW-1 and TCTEL1 and tctex-1, Cytoplasm, DYNLT1 and IDBG-635357 and ENSBTAG00000004472 and 282380, DYNLT1 and IDBG-98463 and ENSG00000146425 and 6993, Tctex-type 1, identical protein binding, light chain, this GO :0000132 and establishment of mitotic spindle orientation and biological process this GO :0003774 and motor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005819 and spindle and cellular component this GO :0005868 and cytoplasmic dynein complex and cellular component this GO :0005874 and microtubule and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0008152 and metabolic process and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0019060 and intracellular transport of viral protein in host cell and biological process this GO :0032314 and regulation of Rac GTPase activity and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046718 and viral entry into host cell and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050768 and negative regulation of neurogenesis and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0075521 and microtubule-dependent intracellular transport of viral material towards nucleus and biological process, this GO :0003774 : motor activity, this GO :0003774 : motor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, dynein |
| Identity: |
11697 |
| Gene: |
DYNLT1 |
More about : DYNLT1 |
| Long gene name: |
dynein light chain Tctex-type 1 |
| Synonyms gene: |
TCTEL1 |
| Synonyms gene name: |
t-complex-associated-testis-expressed 1-like 1 |
| Locus: |
6q25, 3 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
D50663 |
| Entrez gene record: |
6993 |
| Pubmed identfication: |
8646886 16260502 |
| RefSeq identity: |
NM_006519 |
| Classification: |
Dyneins, cytoplasmic |
| Havana BLAST/BLAT: |
OTTHUMG00000015918 |