| Long name: |
ALEXA FLUOR 488 Conjugated, TCTEL1/DYNLT1 Polyclonal Antibody |
| Also known as: |
Anti-TCTEL1/DYNLT1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TCTEL1/DYNLT1 |
| Specificity: |
This is a highly specific antibody against TCTEL1/DYNLT1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TCTEL1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell, Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, Cytoplasmic or axonemal Dynein heavy, It performs functions necessary for cell survival such as organelle transport and centrosome assembly, LIS1 and NudEL(NudE-like), Several proteins regulate Dynein activity, Tctex1, Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A), The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, also designated CW-1 or TCTEL1 is expressed in heart, four smaller intermediate chains and several light chains, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement, ileum and colon, including dynactin, intermediate, kidney, light and light-intermediate chains are all components of minus end-directed motors, ovary, pancreas, placenta, prostate, skeletal muscle, spleen, testis, the complex transports cellular cargos towards the central region of the cell, two intermediate chains to anchor Dynein to its cargo, while the amino terminal regions are more variable, Dyneins are multisubunit |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TCTEL1/DYNLT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
TCTEL1/DYNLT1 |
| Short name: |
TCTEL1/DYNLT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Tctex-classification 1 (Antibody to), light epitope, TCTEL1/dynein |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CW-1 and TCTEL1 and tctex-1, Cytoplasm, DYNLT1 and IDBG-635357 and ENSBTAG00000004472 and 282380, DYNLT1 and IDBG-98463 and ENSG00000146425 and 6993, Tctex-type 1, identical protein binding, light chain, this GO :0000132 and establishment of mitotic spindle orientation and biological process this GO :0003774 and motor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005819 and spindle and cellular component this GO :0005868 and cytoplasmic dynein complex and cellular component this GO :0005874 and microtubule and cellular component this GO :0007067 and mitotic nuclear division and biological process this GO :0008152 and metabolic process and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0019060 and intracellular transport of viral protein in host cell and biological process this GO :0032314 and regulation of Rac GTPase activity and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046718 and viral entry into host cell and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050768 and negative regulation of neurogenesis and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0075521 and microtubule-dependent intracellular transport of viral material towards nucleus and biological process, this GO :0003774 : motor activity, this GO :0003774 : motor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, dynein |
| Identity: |
11697 |
| Gene: |
DYNLT1 |
More about : DYNLT1 |
| Long gene name: |
dynein light chain Tctex-type 1 |
| Synonyms gene: |
TCTEL1 |
| Synonyms gene name: |
t-complex-associated-testis-expressed 1-like 1 |
| Locus: |
6q25, 3 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
D50663 |
| Entrez gene record: |
6993 |
| Pubmed identfication: |
8646886 16260502 |
| RefSeq identity: |
NM_006519 |
| Classification: |
Dyneins, cytoplasmic |
| Havana BLAST/BLAT: |
OTTHUMG00000015918 |